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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB41L4B
All Species:
4.55
Human Site:
T440
Identified Species:
8.33
UniProt:
Q9H329
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H329
NP_060894.2
900
99712
T440
A
A
Q
L
C
S
K
T
N
P
E
V
H
N
Y
Chimpanzee
Pan troglodytes
XP_520178
925
103214
T465
A
A
Q
L
C
S
K
T
N
P
E
V
H
N
Y
Rhesus Macaque
Macaca mulatta
XP_001102639
820
92159
H383
H
P
S
Q
P
R
W
H
P
H
S
P
N
V
S
Dog
Lupus familis
XP_532028
914
101864
F476
N
P
V
I
A
A
Q
F
C
S
K
T
N
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMC8
527
59559
F90
A
T
L
Y
C
R
V
F
L
L
D
G
T
E
V
Rat
Rattus norvegicus
B2RYE5
527
59553
F90
A
T
L
Y
C
R
V
F
L
L
D
G
T
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509941
820
90648
N383
V
P
N
K
D
L
L
N
S
K
E
L
L
E
I
Chicken
Gallus gallus
XP_419046
839
94372
H395
A
K
N
T
P
E
V
H
N
Y
Q
P
Q
Y
H
Frog
Xenopus laevis
NP_001080234
498
57093
K61
D
V
S
V
D
L
P
K
K
A
E
G
Q
E
L
Zebra Danio
Brachydanio rerio
O57457
619
70690
K182
D
S
I
E
Q
I
H
K
T
L
L
G
Q
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650291
972
105216
V413
Q
E
A
A
V
S
A
V
A
S
V
N
A
R
A
Honey Bee
Apis mellifera
XP_623974
809
90976
R372
V
E
E
D
D
E
G
R
G
E
Q
E
H
T
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788387
843
92835
G398
G
Q
T
L
P
S
P
G
G
A
S
A
T
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88
89.1
84.5
N.A.
54.6
54.6
N.A.
35.2
67.1
36.4
25.4
N.A.
33.9
35.3
N.A.
34.6
Protein Similarity:
100
89.8
90
86.9
N.A.
56.6
56.8
N.A.
47.7
75.3
45.4
40.7
N.A.
49.2
52
N.A.
50.1
P-Site Identity:
100
100
0
0
N.A.
13.3
13.3
N.A.
6.6
13.3
6.6
0
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
100
6.6
33.3
N.A.
20
20
N.A.
20
26.6
13.3
6.6
N.A.
6.6
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
16
8
8
8
8
8
0
8
16
0
8
8
0
8
% A
% Cys:
0
0
0
0
31
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
16
0
0
8
24
0
0
0
0
0
16
0
0
0
0
% D
% Glu:
0
16
8
8
0
16
0
0
0
8
31
8
0
31
8
% E
% Phe:
0
0
0
0
0
0
0
24
0
0
0
0
0
0
8
% F
% Gly:
8
0
0
0
0
0
8
8
16
0
0
31
0
0
0
% G
% His:
8
0
0
0
0
0
8
16
0
8
0
0
24
0
8
% H
% Ile:
0
0
8
8
0
8
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
8
0
8
0
0
16
16
8
8
8
0
0
0
0
% K
% Leu:
0
0
16
24
0
16
8
0
16
24
8
8
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
16
0
0
0
0
8
24
0
0
8
16
16
0
% N
% Pro:
0
24
0
0
24
0
16
0
8
16
0
16
0
8
16
% P
% Gln:
8
8
16
8
8
0
8
0
0
0
16
0
24
0
0
% Q
% Arg:
0
0
0
0
0
24
0
8
0
0
0
0
0
8
0
% R
% Ser:
0
8
16
0
0
31
0
0
8
16
16
0
0
8
8
% S
% Thr:
0
16
8
8
0
0
0
16
8
0
0
8
24
8
0
% T
% Val:
16
8
8
8
8
0
24
8
0
0
8
16
0
16
16
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
16
0
0
0
0
0
8
0
0
0
8
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _